Lymphoma is a malignant proliferation of lymphatic system cells. Large B-cell lymphoma is one type of the large list of lymphomas. It could occur in the lymphatic system or other body organs outside it.The clinical expression of this kind of tumors can be really variable. Usely there are general signs such as fever, heavy sweating at night and losing of weight. In addition to symptoms related to the local development of the tumor. In this article, we are about to present a case of tonsillar lymphoma which clinical expression could be confused with any benign tonsillar lesion.

The determination of fetal gender is done for various reasons, including medical reasons such as the diagnosis of sexually transmitted diseases or social causes such as purchases for each gender and the change in the place of residence of the parents. As some of the embryonic diseases are sexually related, the early detection of fetal sex allows parents to make appropriate genetic counselling. If one of the parents or both of them has a definite disease, they can have an early warning about the disease in their fetus, and thus they will be able to decide early on for that fetus. Clinical value is the determination of fetal sex in deciding whether or not to perform prenatal invasive tests (amniocentesis and patchy sampling), because invasive tests are required only in pregnancies that are fetal males. The studies that have been done so far confirm that the best results are obtained in diagnosing fetal sex after 12 weeks of gestation, as a result, invasive tests for the diagnosis of sexually transmitted diseases should only be performed after 12 weeks, because before that the diagnosis of fetal sex is unreliable.

Rosai Dorfman disease (RDD) is rare histiocytic disease with unknown etiology that typically presents with painless cervical lymphadenopathy. The disease is also known as sinus histiocystosis with massive lymphadenopathy (SHML). The normal functioning of lymph glands is disturbed due to significant enlargement of the lymphatic sinuses. Sinus hystiocytes contain cytoplasmic fat and strongly positive S100 protein CD68 and CD14 can be positive. Forty percent of patients have extra nodal involvement. The prognosis of the disease is usually good. However, if accompanied by immunologic abnormalities young age, extra nodal involvement (especially in the kidney or, liver), and the prognosis is poor. Regarding treatment, the disease often has spontaneous remission; therefore, observation is essential. No treatment modalities are superior to over another. In this article, we present a male patient who was diagnosed as having extra nodal RDD with skin and soft tissue involvement, who was followed up for four years.

Introduction: Intussusception signifies the introduction of part of the intestine into adjacent lumen, resulting in intestinal obstruction. The disease has been reported in all ages and even during fetal development, which subsequently led to the absence of intestinal formation; however, it is the most common abdominal emergency and the second most common cause of intestinal obstruction in children under the age of two.

Method: The present descriptive, cross-sectional study was conducted on all patients, diagnosed with intussusception, referring to Amiral-Mo'menin Hospital in Zabol city from 2004 up to 2014. The inclusion criteria were definitive diagnosis in the patient's case. The required information was extracted from the patient records and recorded in the information form. At the end of the study, the information obtained from the information form was analyzed by statistical analysis in the form of frequency of mean standard deviation and other descriptive statistical indices. 

In 2 to 3% of pregnancies, congenital malformations are diagnosed during pregnancy or shortly after birth. These abnormalities, with surpassing premature birth, are the most common cause of death in infants in the United States and account for 20% of these deaths (1). Preventive diagnosis, diagnosis of malformations, fractures, and chromosomal anomalies are some of the most important genetic syndromes in the fetus. Components included within the category of prenatal diagnosis include typical screening tests to find an aneuploidy and neural tube defects, invasive diagnostic tests such as percutaneous and amniocentesis sampling, screening and diagnostic tests suggested to individuals exposed to a specific genetic disorder, and the diagnosis of structural malformations with the help of specialized ultrasound and other methods of embryo imaging. The AFP screening of the mother's serum generally takes place between weeks 15 and 20. This should be done through the protocol, including quality control, consultation and follow- up. The amount of AFP is measured in nano-grams per milliliter and is reported by the median number (MoM) of the non-affected population. Converting outcomes to MoM standardizes AFP level distribution and allows comparison of results from different communities and labs percent reported.