Journal of Medical Practice and Review <p>JMPR invites original research and review articles not published/submitted for publications anywhere. The journal accepts review articles only if author (s) has included his/her own research work and is an authority in the particular field. Invited or submitted review articles on current medical research developments will also be included. Medical practitioners are encouraged to contribute interesting case reports. The journal publishes special features like and book reviews clinical trials which are registered in the Clinical Trial Registry of India or Clinical</p> <p>We publish innovative original research papers, review articles, case reports and short communications dealing with all the medical specialties like Anatomy, Physiology, Biochemistry, Pharmacology, Pathology, Forensic medicine, Microbiology, Community Medicine, Ophthalmology, Otorhinolaryngology, Internal Medicine, General Surgery, Paediatrics, Obstetrics and Gynecology, Orthopedics, Psychiatry, Radiology, Pulmonary Medicine, Dermatology and Venereal diseases, Infectious Diseases, Anaesthesia, Cardiology, Diabetes, Cancer research, Endocrinology, Urology, Neurosurgery, Geriatric Medicine, Gastroenterology, Neurology, Nephrology, Dentistry and Medical education.</p> <p><strong>About US</strong></p> <p>We also accept research articles in the field of Medical Research, Free radical biology, Immunology, Infertility, Hematology, Medical Genetics, Laboratory Medicine, Medical Statistics and Biotechnology</p> <p>Welcome to the Journal of Medical Practice and review, Rapid publication of original medical and allied research articles, reviews, case reports, preliminary and pilot studies. Symposium proceedings, summaries of presentations or collections of medical data on a specific topic are also welcome, for publication as supplements/special issues.</p> Journal of Medical Practice and Review en-US Journal of Medical Practice and Review 2456-267X Biomedical And Epidemiological Features Of Tularemia's Recorded Cases, Its Natural Hotbed, The Prevalence And Distribution Of Redents And Transmitters, During The Period 1996-2012 In Shirak Region <p>Nrensis suggested to call the desease – tularemia. Tularemia has been recorded everywhere &nbsp;in North America, in Japan, in different countries of Europe, in Asia and in Africa. The desease is mainly spread in the landscapes of Northernone. hemisphere's temperature climatic zone. Na­tural breeding ground of Tularemia is confirmed also in the area of Republic of Armenia /90%/.</p> <p>To form the areas of epozootic risk according to the prevalence and density of main carrier and distribution areas of the transmitter, for the assessment of the occurance risk of the special dangerous infections.</p> <p>We have made current and looking-back epidemiological analysis of the deseases with tularemia during 1996-2012 in Shirak region. We use /GIS/ geographical informatioprogramnal system's Arc View GIS 10.0 and Qvantum GIS computer options .</p> <p>Shirak region is included in the geography of Transcaucasion highland plague, tularemia and other special dangerous infections' active natural hotbeds. Gyumri's hotbed's geographical location, climatic conditions and the specific landscape type create favourable conditions for rodents' – ordinary field mouse's and main transmitter's - icsodic tick's survival and repreduction. From 327 types of rodents existing in the area of RA, more than 17 types meet in the area of Gumri's hotbed, in connection with these rodents' ecology there are near 20 types of icsodic and more than 40 gamazic ticks.</p> <p>Shirak region, in this respect, is considered to be risky area, as epizotia's frequency is high. In the hotbed density o5 years – during last f the main holder: ordinary field mouse varied 12-317 in 1 hectare and density of the main transmitter varied 17-130example bloodsucker arthropoda – in 1 hectare. Now, from 16850 persons 3300 person living in Gyumry's hotbed-the most risky area of the infection , form a high risk rating, which are mostly rural. We have formed areas of epizootic risk taking into account epizootical informational data, to assess the occurence risk of special dangerous infections according to the prevalence and density of main bearer and distribution of the transmitter.</p> <p>Mapping of the geographical prevalence of the data is one of the best expressions of situational analysis. In case of goal-oriented organization of antiepidemical measures, it is possible to avoid epidemical complications. New methods and models refine the system of epidemiological control.</p> <p>It is necessary to make detailed analysis of epidemical process taking into account etiological characteristics of infectional deseases. One of the most important factors of elimination of the consequences of epidemics is the early prevision of epidemical situation and beforehand organization of preventive measures.</p> Armine Andryan ##submission.copyrightStatement## 2019-02-15 2019-02-15 3 02 Glycogen Storage Disease Types I, II, III and V – A Mini Review <p>Glycogen storage diseases (GSD) are inherited metabolic disorders of glycogen metabolism. More than 12 types of GSD are known up-to-date and they are classified based on the related enzyme deficiency involved and the affected tissue. In general, GSD affect primarily the liver, the muscle or both but may also affect the kidney and intestine in which the accumulation of glycogen on liver and kidneys results in hepatomegaly and renomegaly. Each type of GSD has a different impact on the metabolism, but some symptoms seem to remain constant between the types; although each one is treated as a unique case. The most common approach to managing GSD is through specific diet. The simplest and most effective long-term treatment for GSD I (Von Gierke’s disease) is by the use of uncooked cornstarch which is able to decrease the metabolic abnormalities of the disease. Recently, Treatment of GSDIa with AAV-GPE-mediated gene therapy in mice has shown promising results in decreasing the metabolic abnormalities and the risk of chronic complications, suggesting that G6Pase-α gene transfer may be a potential therapeutic approach to the management of human GSDIa. The only prominent viable treatment for GSD II (Pompe disease) is through enzyme replacement by gene therapy. Lately, the efficacy of enzyme replacement therapy has improved clinical outcomes but varies between patients and therefore further research is needed. The main treatment of GSD type III (Cori’s disease) is based on diet, through high-protein but limited carbohydrate intake, which can alleviate and even prevent most symptoms. For GSD type V (McArdle disease) there is no cure or treatment, but symptoms can be kept under control. This mini review paper summarizes the value of dietary therapies in improving the quality of life and survival through minimizing metabolic abnormalities and chronic complications.</p> Loannis Patrikios ##submission.copyrightStatement## 2019-02-17 2019-02-17 3 02 Mind control children: Disney’s secret script -a critical review of “inside out”- <p>Inside Out is a film produced by Walt Disney Pictures that won the Oscar for best animated film in 2015, it is very recommended by American psychiatrists however a scientific analysis revels that the film is a promotion of inhuman child mind control with brain nanobots or microchips. The film only can be explained with the secret implantation in Riley’s brain of invasive neurotechnology since fetal life. It is very likely that there are real Riley, girls subject to real mind control, especially in Latin American countries such as Mexico, Argentina and Peru. Although Hollywood arguments are generally attributed to the creativity of their writers and producers, most analysts of&nbsp; films are not aware that the real argument of many films is based on secret and illicit human experiments in the world. This Disney’s mafia becomes rich with the secret and forced use of nanotechnology on human beings at the expense of their health, privacy, honor and even their lives.The world society shall know, be alert and report the crimes committed by this Hollywood’s mafia that aims to become a great organized crime network in the world.</p> David Salinas ##submission.copyrightStatement## 2019-02-18 2019-02-18 3 02